LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

PSMB10

proteasome (prosome, macropain) subunit, beta type, 10

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

Gene Name: proteasome (prosome, macropain) subunit, beta type, 10
Family/Subfamily: Protease Non Catalytic , Threonine T1
Synonyms: PSMB10, Beta2i, Low molecular mass protein 10, MECL1, Proteasome component mecl-1, Proteasome subunit beta-2i, Proteasome subunit beta 7i, Macropain subunit MECl-1, Proteasome MECl-1, LMP10, Proteasome subunit MECL1
Target Sequences: BC017198 NP_002792.1 P40306

Filtered By: None
Target
PSMB10 (19)
Reactivity
Human (19)
Mouse (7)
Rat (7)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Hamster (4)
Monkey (4)
Pig (4)
Application
IHC (6)
IHC-P (3)
WB (18)
ELISA (10)
ICC (1)
IF (4)
Peptide-ELISA (1)
Host
rabbit (17)
mouse (1)
goat (1)
Isotype
IgG (10)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (18)
Clone
3F8 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
Epitope
aa214-242 (8)
aa143-192 (4)
aa231-242 (1)
Publications
No (19)
Showing 1-19 of 19 results

PSMB10 Antibody (aa231-242) IHC-plus™ LS-B10305
Goat Polyclonal to Human PSMB10
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg  $425.00
Anti-PSMB10 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-PSMB10 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PSMB10 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-PSMB10 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PSMB10 Antibody LS-C482445
Rabbit Polyclonal to Human PSMB10
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of PSMB10 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of PSMB10 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Immunohistochemical analysis of PSMB10 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of PSMB10 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.

PSMB10 Antibody LS-C755218
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA IF IHC WB
Unconjugated
100µg  $335.00

PSMB10 Antibody LS-C346083
Rabbit Polyclonal (IgG) to Human PSMB10
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat brain tissue.
Immunohistochemistry of paraffin-embedded mouse brain tissue.
Immunohistochemistry of paraffin-embedded rat brain tissue.
Immunohistochemistry of paraffin-embedded mouse brain tissue.

PSMB10 Antibody (clone 3F8) LS-C198017
Mouse Monoclonal [clone 3F8] (IgG1,k) to Human PSMB10
Human
ELISA IF WB
Unconjugated
100µg  $355.00
Immunofluorescence of monoclonal antibody to PSMB10 on HeLa cell. [antibody concentration 10 ug/ml]
PSMB10 monoclonal antibody (M01), clone 3F8 Western Blot analysis of PSMB10 expression in Jurkat.
Immunofluorescence of monoclonal antibody to PSMB10 on HeLa cell. [antibody concentration 10 ug/ml]
PSMB10 monoclonal antibody (M01), clone 3F8 Western Blot analysis of PSMB10 expression in Jurkat.

PSMB10 Antibody LS-C676317
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100
Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100

PSMB10 Antibody LS-C341799
Rabbit Polyclonal to Human PSMB10
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

PSMB10 Antibody (aa214-242) LS-C324356
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
Unconjugated
200µl  $530.00

PSMB10 Antibody (aa214-242, Biotin) LS-C216999
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

PSMB10 Antibody (aa214-242, FITC) LS-C221188
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
FITC Conjugated
200µl  $680.00

PSMB10 Antibody (aa214-242, AP) LS-C216997
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
AP Conjugated
200µl  $680.00

PSMB10 Antibody (aa214-242, Azide-free, HRP) LS-C217000
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

PSMB10 Antibody (aa214-242, PE) LS-C217001
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
PE Conjugated
200µl  $680.00

PSMB10 Antibody (aa214-242, APC) LS-C216998
Rabbit Polyclonal (IgG) to Human PSMB10
Human
ELISA WB
APC Conjugated
200µl  $680.00

PSMB10 Antibody (aa143-192) LS-C111927
Rabbit Polyclonal to Human PSMB10
Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMB10 Antibody (aa143-192, HRP) LS-C461808
Rabbit Polyclonal to Human PSMB10
Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMB10 Antibody (aa143-192, Biotin) LS-C461806
Rabbit Polyclonal to Human PSMB10
Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMB10 Antibody (aa143-192, FITC) LS-C461807
Rabbit Polyclonal to Human PSMB10
Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PSMB10 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMB10 Antibody (aa214-242) LS-C162228
Rabbit Polyclonal to Human PSMB10
Human
WB
Unconjugated
400µl  $305.00
PSMB10 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The PSMB10 antibody detected the PSMB10 protein (arrow).
PSMB10 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The PSMB10 antibody detected the PSMB10 protein (arrow).
Showing 1-19 of 19 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy