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PSMA1

proteasome (prosome, macropain) subunit, alpha type, 1

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: proteasome (prosome, macropain) subunit, alpha type, 1
Family/Subfamily: Protease Non Catalytic , Threonine T1
Synonyms: PSMA1, 30 kDa prosomal protein, HC2, Macropain subunit C2, NU, PSC2, PROS30, Proteasome nu chain, Proteasome subunit alpha 1, Proteasome subunit nu, Protein P30-33K, Macropain subunit nu, PROS-30, Proteasome component C2
Target Sequences: NM_002786 NP_002777.1 P25786

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PSMA1 (7)
No (7)
GST (1)
His (2)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
PSMA1 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
PSMA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.4 kDa
100 µg/$494
PSMA1 Protein
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E. coli
His, N-Terminal
28.9 kDa
50 µg/$419
PSMA1 Protein
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E. coli
His
32.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PSMA1 Protein - Recombinant Proteasome Subunit Alpha Type 1 By SDS-PAGE
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E. coli
His-T7
31.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
PSMA1 Protein - 12.5% SDS-PAGE of human PSMA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
54.67 kDa
10 µg/$479; 25 µg/$670
PSMA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.4 kDa
20 µg/$150
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).