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PSG2

Pregnancy Specific Beta-1-glycoprotein 2

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Gene Name: Pregnancy Specific Beta-1-glycoprotein 2
Family/Subfamily: CEA , not assigned-CEA
Synonyms: PSG2, Carcinoembryonic antigen SG8, CEA, PS-beta-G-2, PS-beta-E, PSBG-2, PSBG2, PSGGB
Target Sequences: NM_031246 NP_112536.2 P11465

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PSG2 (7)
No (7)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.5kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
PSG2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PSG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37 kDa
20 µg/$150
PSG2 Protein - 12.5% SDS-PAGE of human PSG2 stained with Coomassie Blue
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Wheat Germ Extract
GST
63.6 kDa
10 µg/$479; 25 µg/$670
PSG2 Protein - Recombinant Pregnancy Specific Beta-1-Glycoprotein 2 By SDS-PAGE
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E. coli
His-T7
37.2 kDa
10 µg/$261; 50 µg/$337; 100 µg/$507; 200 µg/$632; 1 mg/$1,609; 500 µg/$1,201; 5 mg/$2,546; 2 mg/$1,781
PSG2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.5 kDa
10 µg/$344; 50 µg/$584
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).