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PSAP / Prosaposin

prosaposin

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.

Gene Name: prosaposin
Synonyms: PSAP, Cerebroside sulfate activator, GLBA, Proactivator polypeptide, Prosaposin, SAP1
Target Sequences: NM_002778 NP_002769.1 P07602

☰ Filters
Antibodies (44)
ELISA Kits (18)
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PSAP / Prosaposin (75)
Human (46)
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rabbit (36)
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monoclonal mc (9)
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PSAP / Prosaposin Antibody - Anti-PSAP / Prosaposin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PSAP / Prosaposin Mouse anti-Human Monoclonal (4D5F4) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PSAP / Prosaposin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
PSAP / Prosaposin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PSAP / Prosaposin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PSAP / Prosaposin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Seminal Plasma
1 Plate/$834
PSAP / Prosaposin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$913
PSAP / Prosaposin Antibody - Immunohistochemistry of paraffin-embedded human liver tissue.
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PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PSAP / Prosaposin Antibody - Anti-PSAP antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Cancer Pathology
Cancer
PSAP / Prosaposin Mouse anti-Human Monoclonal (1D1-C12) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$485
PSAP / Prosaposin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
PSAP / Prosaposin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa17-524) Antibody
Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
PSAP / Prosaposin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PSAP / Prosaposin ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PSAP / Prosaposin Antibody - PSAP Antibody in Immunohistochemistry (IHC)
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PSAP / Prosaposin Mouse anti-Human Monoclonal (Amino Acid: 325-524) (4D5F4) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
PSAP / Prosaposin Antibody - IHC of PSAP on FFPE Prostate tissue.
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PSAP / Prosaposin Mouse anti-Human Monoclonal (PASE/4LJ) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$298
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PSAP / Prosaposin Rabbit anti-Mouse Monoclonal (Preservative Free) (003) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
PSAP / Prosaposin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa307-356) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
PSAP / Prosaposin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa291-340) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
PSAP / Prosaposin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
Select
PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PSAP / Prosaposin Antibody
Select
PSAP / Prosaposin Mouse anti-Human Monoclonal (PSPN1-1) Antibody
Human
Flo, IF, IHC
Unconjugated
20 µg/$371; 100 µg/$574
PSAP / Prosaposin Antibody -  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
PSAP / Prosaposin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (PSPN1-1) Antibody
Human
Flo, IF, IHC
Unconjugated, Azide-free, BSA-free
100 µg/$574
PSAP / Prosaposin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa1-250) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µl/$485
Viewing 1-25 of 75 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).