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PRTN3 / Myeloblastin
proteinase 3
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
| Gene Name: | proteinase 3 |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | PRTN3, ACPA, Azurophil granule protein 7, C-ANCA antigen, CANCA, C-ANCA, AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, NP4, p29, PR-3, Proteinase 3, MBT, Wegener autoantigen, PR3, Serine proteinase, neutrophil |
| Target Sequences: | NM_002777 NP_002768.3 P24158 |
Publications (3)
1
IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. Johnston A, Xing X, Wolterink L, Barnes DH, Yin Z, Reingold L, Kahlenberg JM, Harms PW, Gudjonsson JE. The Journal of allergy and clinical immunology. 2017 July;140:109-120. [Full Text Article]
[PubMed:28043870]
[PMC:PMC5494022]
2
Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation. Yang TH, St John LS, Garber HR, Kerros C, Ruisaard KE, Clise-Dwyer K, Alatrash G, Ma Q, Molldrem JJ. Journal of immunology (Baltimore, Md. : 1950). 2018 September;201:1389-1399. [Full Text Article]
[PubMed:30021768]
[PMC:PMC6099529]
Related Antibodies: LS-C38480.
3
Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression. Agnieszka Fatalska, Natalia Rusetska, Elwira Bakula-Zalewska, Artur Kowalik, Sebastian Zieba, Agnieszka Wroblewska, Kamil Zalewski, Krzysztof Goryca, Dominik Domanski, Magdalena Kowalewska. Cancers. 2020 December;13: [Full Text Article]
[PubMed:33374674]
[PMC:PMC7793473]
☰ Filters
Products
ELISA Kits
(18)
Type
Custom
(1)
Sandwich
(15)
Sandwich CLIA
(2)
Target
PRTN3 / Myeloblastin
(18)
Reactivity
Human
(9)
Mouse
(2)
Rat
(2)
Chicken
(1)
Guinea pig
(1)
Monkey
(1)
Porcine
(1)
Rabbit
(1)
Format
12 x 8-Well Microstrips
(2)
96-Well Microplate
(2)
96-Well Strip Plate
(14)
Publications
No
(17)
Yes
(1)
Sample Type
Cell Culture Supernatants
(1)
EDTA Plasma
(1)
Heparin Plasma
(1)
Plasma
(11)
Serum
(12)
Tissue Homogenates
(2)
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$923
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Chicken
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich CLIA
12 x 8-Well Microstrips
Rat
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Rat
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$856
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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