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PRSS16
protease, serine, 16 (thymus)
PRSS16 is a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.
| Gene Name: | protease, serine, 16 (thymus) |
| Family/Subfamily: | Exopeptidase , Serine S28 |
| Synonyms: | PRSS16, Protease, serine, 16 (thymus), Serine protease 16, TSSP |
| Target Sequences: | NM_005865 NP_005856.1 Q9NQE7 |
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