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PRSS1 / Trypsin

protease, serine, 1 (trypsin 1)

PRSS1 / Trypsin is a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

Gene Name: protease, serine, 1 (trypsin 1)
Family/Subfamily: Protease , Serine S1
Synonyms: PRSS1, Beta-trypsin, Cationic trypsinogen, Digestive zymogen, HPC, Hereditary pancreatitis, TRP1, TRY4, Trypsin, Trypsinogen i, TRYP1, Trypsinogen, TRY1, Trypsinogen 1, Nonfunctional trypsin 1, Protease serine 1, Serine protease 1, Trypsin I, Trypsin-1, Trypsinogen A
Target Sequences: NM_002769 NP_002760.1 P07477

Publications (1)

1
Barnacle cement: a polymerization model based on evolutionary concepts. Dickinson GH, Vega IE, Wahl KJ, Orihuela B, Beyley V, Rodriguez EN, Everett RK, Bonaventura J, Rittschof D. The Journal of experimental biology. 2009 212:3499-510. [PubMed:19837892] [PMC:PMC2762877]

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Antibodies (65)
Primary (65)
PRSS1 / Trypsin (65)
Human (46)
Mouse (17)
Rat (8)
Bovine (15)
Chimpanzee (3)
Gibbon (3)
Horse (3)
IHC (9)
IHC-P (5)
WB (49)
DB (2)
ELISA (42)
ID (3)
IE (4)
IF (2)
Inhb (3)
IP (4)
Peptide-ELISA (2)
rabbit (61)
mouse (3)
sheep (1)
Product Group
IHCPlus (2)
PathPlus Other (1)
IgG (39)
IgG1 (1)
IgG2b (2)
monoclonal mc (3)
polyclonal pc (62)
102043 (1)
APC (1)
APC Conjugated (3)
Biotin Conjugated (11)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
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Liquid (3)
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PE Conjugated (3)
Unconjugated (30)
aa51-228 (8)
aa81-107 (7)
N-Terminus (5)
C-Terminus (4)
Internal (2)
Met109 (1)
aa16-247 (1)
aa60-109 (1)
No (65)
PRSS1 / Trypsin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal (aa81-107) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PRSS1 / Trypsin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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PRSS1 / Trypsin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$884
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PRSS1 / Trypsin Rabbit anti-Rat Polyclonal (HRP) Antibody
Rat
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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PRSS1 / Trypsin Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, ID, IE, Inhb, WB
Unconjugated
1 mg/$890
PRSS1 / Trypsin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Lyophilized) Antibody
Bovine
ELISA, IHC-P, WB
Unconjugated, Lyophilized
100 µg/$567
PRSS1 / Trypsin Antibody - PRSS1 / Trypsin antibody Western blot of HT1080 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PRSS1 / Trypsin Antibody - PRSS1 / Trypsin antibody Western blot of HT1080 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
PRSS1 / Trypsin Antibody - PRSS1 / Trypsin antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$469
PRSS1 / Trypsin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Biotin) Antibody
Bovine
ELISA, IF, IHC, WB
Biotin Conjugated
100 µg/$896
PRSS1 / Trypsin Antibody - Dot Blot results of rabbit Anti-Trypsin Peroxidase Conjugated. Antigen: Trypsin. Blot loaded at 3 fold dilution: 1. 100ng, 2. 33.3ng, 3. 11.1ng, 4. 3.70ng, 5. 1.23ng. Blocking: MB-070 Buffer for 30 minutes at RT. Primary Antibody: Rabbit Anti-Trypsin HRP 10µg/mL for 1hr at RT. Secondary Antibody: none. Imaging System ChemiDoc, Filter used: Chemi.
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Lyophilized) (HRP) Antibody
Bovine
DB, ELISA, IHC, WB
HRP Conjugated, Lyophilized
100 µg/$552
PRSS1 / Trypsin Antibody - Dot Blot results of rabbit Anti-Trypsin Peroxidase Conjugated. Antigen: Trypsin. Blot loaded at 3 fold dilution: 1. 100ng, 2. 33.3ng, 3. 11.1ng, 4. 3.70ng, 5. 1.23ng. Blocking: MB-070 Buffer for 30 minutes at RT. Primary Antibody: Rabbit Anti-Trypsin HRP 10µg/mL for 1hr at RT. Secondary Antibody: none. Imaging System ChemiDoc, Filter used: Chemi.
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Liquid) (HRP) Antibody
Bovine
DB, ELISA, IHC, WB
HRP Conjugated, Liquid
25 µl/$304
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, ID, IE, Inhb, WB
Unconjugated
5 mg/$558
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IHC, WB
Unconjugated
2 ml/$1,225
PRSS1 / Trypsin Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
PRSS1 / Trypsin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IE, WB
Unconjugated
1 ml/$495; 10 ml/$2,645
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PRSS1 / Trypsin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Biotin) Antibody
Bovine
ELISA, ID, IE, Inhb, WB
Biotin Conjugated
1 ml/$688
PRSS1 / Trypsin Antibody - Western Blot of Rabbit anti-Trypsin Antibody Biotin Conjugated. Lane 1: Trypsin. Load: 50 ng per lane. Primary antibody: Rabbit anti-Trypsin Antibody Biotin Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: HRP streptavidin secondary antibody at 1:40,000 for 30 min at RT.
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Lyophilized) (Biotin) Antibody
Bovine
ELISA, IHC, WB
Biotin Conjugated, Lyophilized
100 µg/$552
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PRSS1 / Trypsin Sheep anti-Human Polyclonal (aa16-247) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$930
PRSS1 / Trypsin Antibody - Western Blot of rabbit anti-Trypsin Antibody Biotin Conjugated. Lane 1: Trypsin. Load: 50 ng per lane. Primary antibody: Rabbit anti-Trypsin Antibody Biotin Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: HRP streptavidin secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 minutes at RT. Predicted/Observed size: 26 kDa, 26 kDa for Trypsin. Other band(s): autocatalytic fragment of Trypsin, ~10 kDa.
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal (Liquid) (Biotin) Antibody
Bovine
ELISA, IHC, WB
Biotin Conjugated, Liquid
25 µl/$304
Select
PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IP, WB
Unconjugated
100 µg/$973
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PRSS1 / Trypsin Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, IP, WB
Unconjugated
100 µg/$973
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).