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PRSS1 / Trypsin

protease, serine, 1 (trypsin 1)

PRSS1 / Trypsin is a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

Gene Name: protease, serine, 1 (trypsin 1)
Family/Subfamily: Protease , Serine S1
Synonyms: PRSS1, Beta-trypsin, Cationic trypsinogen, Digestive zymogen, HPC, Hereditary pancreatitis, TRP1, TRY4, Trypsin, Trypsinogen i, TRYP1, Trypsinogen, TRY1, Trypsinogen 1, Nonfunctional trypsin 1, Protease serine 1, Serine protease 1, Trypsin I, Trypsin-1, Trypsinogen A
Target Sequences: NM_002769 NP_002760.1 P07477

Publications (1)

1
Barnacle cement: a polymerization model based on evolutionary concepts. Dickinson GH, Vega IE, Wahl KJ, Orihuela B, Beyley V, Rodriguez EN, Everett RK, Bonaventura J, Rittschof D. The Journal of experimental biology. 2009 212:3499-510. [PubMed:19837892] [PMC:PMC2762877]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).