PRPK / TP53RK

TP53 regulating kinase

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP By similarity. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PRPK / TP53RK (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PRPK / TP53RK Protein (Recombinant GST, N-terminus) (aa154-253) - LS-G63525

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PRPK / TP53RK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92454

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

20 µg/$150

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Human PRPK / TP53RK Protein (Recombinant GST) (Full Length) - LS-G36139

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.57 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PRPK / TP53RK Protein (Recombinant His, N-Terminal) - LS-G144014

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28 kDa

Price:

50 µg/$419

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PRPK / TP53RK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102147

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

100 µg/$494

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