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PRPK / TP53RK

TP53 regulating kinase

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP By similarity. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.

Gene Name: TP53 regulating kinase
Family/Subfamily: Protein Kinase , Bud32
Synonyms: TP53RK, C20orf64, BUD32, DJ101A2.2, DJ101A2, Nori-2p, p53-related protein kinase, PRPK, TP53-regulating kinase, Nori-2, TP53 regulating kinase
Target Sequences: NM_033550 NP_291028.3 Q96S44

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Products
Antibodies (38)
Primary (38)
PRPK / TP53RK (38)
Human (38)
Mouse (15)
Rat (2)
IHC (15)
IHC-P (6)
WB (36)
ELISA (20)
rabbit (27)
mouse (11)
Product Group
IHCPlus (1)
IgG (20)
IgG1 (4)
IgG1,k (2)
IgG2a (3)
IgG2b (2)
monoclonal mc (11)
polyclonal pc (27)
2E8 (1)
4B9-1H3 (1)
OTI4D10 (2)
OTI5A5 (1)
OTI5B2 (2)
OTI5G7 (2)
OTI6A8 (2)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (4)
Carrier-free (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (20)
aa100-128 (7)
aa220-249 (7)
aa221-250 (7)
N-Terminus (4)
No (38)
PRPK / TP53RK Antibody - Anti-TP53RK antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PRPK / TP53RK Mouse anti-Human Monoclonal (4B9-1H3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PRPK / TP53RK Antibody - IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)(1:150).
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PRPK / TP53RK Mouse anti-Human Monoclonal (OTI5B2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRPK / TP53RK Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min. (1:150)
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PRPK / TP53RK Mouse anti-Human Monoclonal (Carrier-free) (OTI5B2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRPK / TP53RK Antibody - Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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PRPK / TP53RK Mouse anti-Human Monoclonal (OTI5G7) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
PRPK / TP53RK Antibody - Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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PRPK / TP53RK Mouse anti-Human Monoclonal (Carrier-free) (OTI5G7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRPK / TP53RK Antibody - IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)(1:150).
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PRPK / TP53RK Mouse anti-Human Monoclonal (OTI5A5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRPK / TP53RK Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PRPK / TP53RK Rabbit anti-Human Polyclonal (aa220-249) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PRPK / TP53RK Antibody - IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)(1:150).
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PRPK / TP53RK Mouse anti-Human Monoclonal (OTI4D10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRPK / TP53RK Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TP53RK mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min. (1:150)
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PRPK / TP53RK Mouse anti-Human Monoclonal (Carrier-free) (OTI4D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
PRPK / TP53RK Rabbit anti-Human Polyclonal (aa221-250) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PRPK / TP53RK Rabbit anti-Human Polyclonal (aa221-250) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PRPK / TP53RK Rabbit anti-Human Polyclonal (aa221-250) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PRPK / TP53RK Antibody - Mouse Tp53rk Antibody western blot of HepG2 cell line lysates (35 ug/lane). The Tp53rk antibody detected the Tp53rk protein (arrow).
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PRPK / TP53RK Rabbit anti-Mouse Polyclonal (aa100-128) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 38 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).