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PRPF8

pre-mRNA processing factor 8

Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.

Gene Name: pre-mRNA processing factor 8
Synonyms: PRPF8, Apoptosis-regulated protein 1, p220, PRP8 homolog, PRP8, PRPC8, RP13, Splicing factor Prp8, Apoptosis-regulated protein 2, HPRP8
Target Sequences: NM_006445 NP_006436.3 Q6P2Q9

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PRPF8 Protein - 12.5% SDS-PAGE of human PRPF8 stained with Coomassie Blue
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Wheat Germ Extract
GST
58.1 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).