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PRPF6 / TOM
pre-mRNA processing factor 6
Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
| Gene Name: | pre-mRNA processing factor 6 |
| Synonyms: | PRPF6, ANT1, C20orf14, BB152O15.1, HPrp6, Prp6, PRP6 homolog, TOM, U5-102K, Pre-mRNA-processing factor 6, ANT-1, U5-102 kDa protein |
| Target Sequences: | NM_012469 NP_036601.2 O94906 |
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