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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PROX1

prospero homeobox 1

Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Gene Name: prospero homeobox 1
Synonyms: PROX1, Prospero-related homeobox 1, Prospero homeobox 1, PROX-1, Prospero homeobox protein 1
Target Sequences: NM_002763 NP_002754.2 Q92786

Filtered by: None
Target
PROX1 (61)
Reactivity
Human (61)
Mouse (32)
Rat (5)
Bat (5)
Bovine (2)
Chicken (5)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (1)
Hamster (1)
Horse (2)
Monkey (6)
Pig (1)
Rabbit (2)
Sheep (1)
Application
IHC (31)
IHC-P (3)
WB (56)
Flo (12)
ELISA (37)
IF (5)
Peptide-ELISA (1)
Host
rabbit (57)
mouse (4)
Isotype
IgG (49)
IgG1 (1)
IgG2b,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (57)
Clone
1E7 (1)
5G10 (2)
Format
AP Conjugated (5)
APC Conjugated (5)
Azide-free (4)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (25)
Epitope
aa144-175 (8)
aa492-520 (8)
aa492-522 (8)
aa185-214 (7)
aa303-352 (4)
aa196-215 (1)
aa346-359 (1)
aa444-478 (1)
Publications
No (61)
Showing 1-25 of 61 results

PROX1 Antibody (aa492-522) LS-C97698
Rabbit Polyclonal to Human PROX1
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Fluorescent confocal image of A2058 cell stained with PROX1 Antibody. A2058 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with PROX1 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). PROX1 immunoreactivity is localized to Nucleus significantly.
PROX1 Antibody (K507) western blot of A2058 cell line lysates (35 ug/lane). The PROX1 antibody detected the PROX1 protein (arrow).

PROX1 Antibody (aa492-520) LS-C162172
Rabbit Polyclonal to Human PROX1
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
PROX-1-S514 Antibody IHC of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of lysates from HepG2 cell line and mouse liver tissue lysate(from left to right), using PROX-1 Antibody (S514). Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

PROX1 Antibody (aa492-520) LS-C324313
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

PROX1 Antibody (aa492-520, Biotin) LS-C267176
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

PROX1 Antibody (aa492-520, FITC) LS-C267177
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

PROX1 Antibody (aa492-520, APC) LS-C267175
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

PROX1 Antibody (aa492-520, AP) LS-C267174
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

PROX1 Antibody (aa492-520, PE) LS-C267180
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

PROX1 Antibody (aa492-520, Azide-free, HRP) LS-C267178
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

PROX1 Antibody (clone 1E7) LS-C198008
Mouse Monoclonal [clone 1E7] (IgG2b,k) to Human PROX1
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to PROX1 on HeLa cell . [antibody concentration 10 ug/ml]
Detection limit for recombinant GST tagged PROX1 is approximately 1 ng/ml as a capture antibody.

PROX1 Antibody (clone 5G10) LS-C150339
Mouse Monoclonal [clone 5G10] (IgG1) to Human PROX1
Chicken, Mouse, Rat, Human
IHC, IHC-P
Unconjugated
100µl  $375.00
IHC of rat dentate gyrus showing specific immunolabeling of the prox1 protein. Photo courtesy of Justin Kievits and Teresa Milner, Weill Cornell Medical College.

PROX1 Antibody LS-C752527
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg  $355.00

PROX1 Antibody LS-C752530
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg  $335.00

PROX1 Antibody LS-C752529
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg  $355.00

PROX1 Antibody LS-C331389
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
Flo, IHC, WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts from Hela cell and mouse brain.
Western blot analysis of extracts of mouse eye, using PROX1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.

PROX1 Antibody (aa185-214) LS-C328399
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

PROX1 Antibody (aa185-214, FITC) LS-C281677
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

PROX1 Antibody (aa185-214, AP) LS-C281672
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

PROX1 Antibody (aa492-522) LS-C328400
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

PROX1 Antibody (aa492-522, FITC) LS-C281669
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

PROX1 Antibody (aa492-522, AP) LS-C281666
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

PROX1 Antibody (aa492-522, APC) LS-C281667
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

PROX1 Antibody (aa492-522, Azide-free, HRP) LS-C281670
Rabbit Polyclonal (IgG) to Human PROX1
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

PROX1 Antibody LS-C769873
Rabbit Polyclonal (IgG) to Human PROX1
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl 0.8mg/ml  $205.00; 60µl 0.8mg/ml  $235.00; 120µl 0.8mg/ml  $295.00; 200µl 0.8mg/ml  $395.00

PROX1 Antibody LS-C152954
Mouse Monoclonal (IgG) to Human PROX1
Chicken, Mouse, Rat, Human
IHC, WB
Unconjugated
100µg  $475.00
Showing 1-25 of 61 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).