PROX1

prospero homeobox 1

Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PROX1 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human PROX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76545

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83 kDa

Price:

20 µg/$150

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Human PROX1 Protein (Recombinant GST, N-terminus) (aa638-737) - LS-G59765

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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PROX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99862

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83 kDa

Price:

100 µg/$494

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