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Proteoglycan 4 / Lubricin

proteoglycan 4

Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages.

Gene Name: proteoglycan 4
Synonyms: PRG4, BG174L6.2, CACP, HAPO, JCAP, Proteoglycan 4, Superficial zone proteoglycan, SZP, Lubricin, MSF
Target Sequences: NM_005807 NP_005798.3 Q92954

Publications (2)

1
Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage. Hasegawa A, Yonezawa T, Taniguchi N, Otabe K, Akasaki Y, Matsukawa T, Saito M, Neo M, Marmorstein LY, Lotz MK. Arthritis and rheumatism. 2017 March;69:576-585. (Human) [Full Text Article] [PubMed:27780308] [PMC:PMC5328782]
2
Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine. Ling Yu, Yu-Lieh Lin, Mingquan Yan, Tao Li, Emily Y Wu, Katherine Zimmel, Osama Qureshi, Alyssa Falck, Kirby M Sherman, Shannon S Huggins, Daniel Osorio Hurtado, Larry J Suva, Dana Gaddy, James Cai, Regina Brunauer, Lindsay A Dawson, Ken Muneoka. Development (Cambridge, England). 2022 January;149:dev200249. [Full Text Article] [PubMed:35005773] [PMC:PMC8917415]

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Products
ELISA Kits (12)
Sandwich (11)
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Proteoglycan 4 / Lubricin (12)
Human (5)
Mouse (1)
Rat (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (10)
No (12)
Plasma (7)
Serum (7)
Synovial Fluid (1)
Tissue Homogenates (3)
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Microplate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Synovial Fluid
1 Plate/$854
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
Proteoglycan 4 / Lubricin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).