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Proteoglycan 4 / Lubricin

proteoglycan 4

Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages.

Gene Name: proteoglycan 4
Synonyms: PRG4, BG174L6.2, CACP, HAPO, JCAP, Proteoglycan 4, Superficial zone proteoglycan, SZP, Lubricin, MSF
Target Sequences: NM_005807 NP_005798.3 Q92954

Publications (2)

1
Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage. Hasegawa A, Yonezawa T, Taniguchi N, Otabe K, Akasaki Y, Matsukawa T, Saito M, Neo M, Marmorstein LY, Lotz MK. Arthritis and rheumatism. 2017 March;69:576-585. (Human) [Full Text Article] [PubMed:27780308] [PMC:PMC5328782]
2
Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine. Ling Yu, Yu-Lieh Lin, Mingquan Yan, Tao Li, Emily Y Wu, Katherine Zimmel, Osama Qureshi, Alyssa Falck, Kirby M Sherman, Shannon S Huggins, Daniel Osorio Hurtado, Larry J Suva, Dana Gaddy, James Cai, Regina Brunauer, Lindsay A Dawson, Ken Muneoka. Development (Cambridge, England). 2022 January;149:dev200249. [Full Text Article] [PubMed:35005773] [PMC:PMC8917415]

☰ Filters
Antibodies (16)
ELISA Kits (12)
Proteins (2)
Primary (16)
Recombinant (2)
Sandwich (11)
Sandwich CLIA (1)
Proteoglycan 4 / Lubricin (30)
Human (21)
Mouse (4)
Rat (4)
Chicken (1)
Guinea pig (1)
Monkey (2)
Porcine (1)
Rabbit (1)
IHC (1)
IHC-P (1)
WB (15)
ELISA (2)
ICC (1)
IF (1)
IP (1)
Peptide-ELISA (2)
rabbit (14)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
Ig (1)
IgG (4)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (15)
1D5 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (10)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (9)
aa1151-1241 (8)
N-Terminus (2)
aa99-110 (1)
No (30)
Plasma (7)
Serum (7)
Synovial Fluid (1)
Tissue Homogenates (3)
6His, N-terminus (1)
GST, N-terminus (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
Proteoglycan 4 / Lubricin Antibody
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$332
Select
Proteoglycan 4 / Lubricin Goat anti-Human Polyclonal (aa99-110) Antibody
Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$401
Proteoglycan 4 / Lubricin Antibody - Detection limit for recombinant GST tagged PRG4 is approximately 3 ng/ml as a capture antibody.
Select
Proteoglycan 4 / Lubricin Mouse anti-Human Monoclonal (1D5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Proteoglycan 4 / Lubricin Protein - Recombinant Proteoglycan 4 By SDS-PAGE
Select
E. coli
6His, N-terminus
11.6 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
200 µl/$468
Proteoglycan 4 / Lubricin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) Antibody
Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Synovial Fluid
1 Plate/$854
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Proteoglycan 4 / Lubricin Antibody - Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized Hela (human cervical epithelial adenocarcinoma cell line) cells labeling PRG4 with PRG4 Antibody (N-Term) at 1/25 dilution, followed by Dylight® 488-conjugated goat anti-rabbit IgG (1583138) secondary antibody at 1/200 dilution (green). Immunofluorescence image showing cytoplasm staining on Hela cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin (PD18466410) at 1/100 dilution (red).The nuclear counter stain is DAPI (blue).
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$393
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Proteoglycan 4 / Lubricin Antibody - Western blot analysis of extracts of LO2 cells, using PRG4 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Proteoglycan 4 / Lubricin Antibody - Western Blot; Sample: Recombinant PRG4, Human.
Select
Proteoglycan 4 / Lubricin Rabbit anti-Human Polyclonal (aa1151-1241) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Proteoglycan 4 / Lubricin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Viewing 1-25 of 30 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).