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Prostaglandin D Synthase

prostaglandin D2 synthase 21kDa (brain)

Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Gene Name: prostaglandin D2 synthase 21kDa (brain)
Synonyms: PTGDS, Beta-trace protein, LPGDS, PGD2, PGD2 synthase, PGDS, Prostaglandin D synthase, Prostaglandin-D2 synthase, L-PGDS, PDS, Cerebrin-28, PGDS2, Prostaglandin-H2 D-isomerase
Target Sequences: NM_000954 NP_000945.3 P41222

Publications (1)

1
Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes. Takeda K, Takahashi NH, Yoshizawa M, Shibahara S. Journal of biochemistry. 2010 148:139-48. (WB; Human) [PubMed:20403807]

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ELISA Kits (18)
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Prostaglandin D Synthase (18)
Human (6)
Mouse (5)
Rat (2)
Dog (1)
Monkey (2)
Pig (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (1)
96-Well Strip Plate (14)
No (18)
Cerebrospinal Fluid (1)
Plasma (12)
Serum (12)
Tissue Homogenates (4)
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Prostaglandin D Synthase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cerebrospinal Fluid, Plasma, Serum
1 Plate/$764
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Prostaglandin D Synthase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
Prostaglandin D Synthase ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
Prostaglandin D Synthase ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
Prostaglandin D Synthase ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
Prostaglandin D Synthase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Prostaglandin D Synthase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Prostaglandin D Synthase ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
4.7 - 300 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).