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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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PROK1 / EG-VEGF
prokineticin 1
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
| Gene Name: | prokineticin 1 |
| Synonyms: | PROK1, EG-VEGF, EGVEGF, Mambakine, PRK1, Prokineticin-1, PK1, Prokineticin 1 |
| Target Sequences: | NM_032414 NP_115790.1 P58294 |
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