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PROCR / EPCR

protein C receptor, endothelial

PROCR / EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Gene Name: protein C receptor, endothelial
Synonyms: PROCR, Activated protein C receptor, CD201, CD201 antigen, Centrocyclin, CCD41, Endothelial protein C receptor, APC receptor, BA42O4.2, CCCA, EPCR
Target Sequences: NM_006404 NP_006395.2 Q9UNN8

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).