PRNP / PrP / Prion

prion protein

PRNP / PrP / Prion is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.

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Products

Proteins (9)

Type

Recombinant (9)

Target

PRNP / PrP / Prion (9)

Application

SDS-PAGE (1)

Publications

No (9)

Tag

GST (2)

His (4)

His, N-Terminal (2)

Human IgG Fc, C-terminus (1)

Species

Human (6)

Mouse (1)

Rat (2)

Source

E. coli (5)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human PRNP / PrP / Prion Protein (Recombinant His) - LS-G2232

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Mouse PRNP / PrP / Prion Protein (Recombinant His, N-Terminal) (aa23-230) - LS-G14138

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

26.8 kDa

Price:

10 µg/$284; 50 µg/$462; 200 µg/$922; 1 mg/$2,042; 5 mg/$3,221; 2 mg/$2,231

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Rat PRNP / PrP / Prion Protein (Recombinant His) (aa29-231) - LS-G23086

Source:

Yeast

Tag:

His

Molecular Weight:

24.25 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human PRNP / PrP / Prion Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Gly229) - LS-G47660

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human PRNP/Fc comprises 448 amino acids and has a predicted molecular mass of 49.7 kDa. The apparent molecular mass of the protein is approximately 57.4 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$480

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Human PRNP / PrP / Prion Protein (Recombinant His, N-Terminal) (aa23-230) - LS-G14140

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

26.6 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Rat PRNP / PrP / Prion Protein (Recombinant His) (aa29-231) - LS-G21081

Source:

E. coli

Tag:

His

Molecular Weight:

26.34 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human PRNP / PrP / Prion Protein (Recombinant GST) (Full Length) - LS-G29937

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.1 kDa

Price:

2 µg/$439

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Human PRNP / PrP / Prion Protein (Recombinant GST) (Full Length) - LS-G29936

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.57 kDa

Price:

2 µg/$439

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Human PRNP / PrP / Prion Protein (Recombinant His) (aa23-110) - LS-G140900

Source:

E. coli

Sequence Length:

87 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

9.68 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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