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PRND / DOPPEL is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.
Gene Name: | prion protein 2 (dublet) |
Synonyms: | PRND, DOPPEL, DJ1068H6.4, DPL, Prion protein 2, Prion protein 2 (dublet), Prion gene complex, downstream, Prion-like protein doppel, PrPLP |
Target Sequences: | NM_012409 NP_036541.2 Q9UKY0 |
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