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PRMT8

protein arginine methyltransferase 8

Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.

Gene Name:	protein arginine methyltransferase 8
Synonyms:	PRMT8, HRMT1L3, HRMT1L4
Target Sequences:	NM_019854 NP_062828.3 Q9NR22

Publications (1)

7p21.3 Together With a 12p13.32 Deletion in a Patient With Microcephaly-Does 12p13.32 Locus Possibly Comprises a Candidate Gene Region for Microcephaly?. Martina Rincic, Milan Rados, Janja Kopic, Zeljka Krsnik, Thomas Liehr. Frontiers in molecular neuroscience. 2021 February;14:613091. [Full Text Article] [PubMed:33613193] [PMC:PMC7890232] Related Antibodies: LS-C328308.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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