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PRIM2 / DNA Primase
primase, DNA, polypeptide 2 (58kDa)
PRIM2 / DNA Primase is the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6.
| Gene Name: | primase, DNA, polypeptide 2 (58kDa) |
| Synonyms: | PRIM2, DNA primase large subunit, DNA primase subunit p58, DJ422B11.1.1, p58, Primase polypeptide 2A, 58kDa, PRIM2A, Primase, polypeptide 2A, 58kDa, DNA Primase, DNA primase 58 kDa subunit, Primase, polypeptide 2A (58kD) |
| Target Sequences: | NM_000947 NP_000938.2 P49643 |
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