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PRAME

preferentially expressed antigen in melanoma

PRAME encodes a 509 amino acid antigen, lacking a signal sequence, and recognized on a human melanoma cell line by a T-lymphocyte clone. A significant level of PRAME mRNA is detected in normal testis as well as in many melanomas, non-small cell lung carcinomas, sarcomas, head and neck tumors and renal carcinomas. PRAME is expressed predominantly in acute leukemias carrying chromosomal abnormalities such as translocation t(8:21), which fuses the AML1 and ETO genes. PRAME expression shares several characteristics with the expression patterns of MAGE, BAGE, and GAGE gene families, all of which are expressed in tumors. PRAME is expressed in a higher proportion of samples than genes of the MAGE, BAGE, and GAGE families, and of these four groups, only PRAME is expressed by acute myeloid leukemias.

Gene Name: preferentially expressed antigen in melanoma
Synonyms: PRAME, Cancer/testis antigen 130, CT130, MAPE, Opa-interacting protein 4, Opa-interacting protein OIP4, OIP-4, OIP4
Target Sequences: NM_006115 NP_006106.1 P78395

☰ Filters
Antibodies (36)
Proteins (16)
ELISA Kits (4)
Custom (1)
Development Kit (1)
Over-Expression Lysate (10)
Primary (36)
Recombinant (6)
Sandwich (2)
PRAME (56)
Human (40)
Mouse (2)
Rat (4)
Bovine (4)
Dog (1)
Gibbon (6)
Horse (4)
Monkey (4)
Pig (6)
Rabbit (3)
IHC (7)
IHC-P (5)
WB (30)
Flo (1)
ELISA (6)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (36)
Product Group
DevKit DuoPlus (1)
IgG (10)
polyclonal pc (36)
96-Well Strip Plate (3)
Antibody Pair and Standard (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (13)
aa416-502 (16)
N-Terminus (4)
aa1-509 (4)
aa71-120 (4)
aa1-300 (1)
aa476-502 (1)
No (56)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (1)
Serum (1)
Tissue Homogenates (3)
6His, N-terminus (1)
GST (1)
His (2)
His-GST (1)
Myc-DDK (Flag) (11)
Human (11)
293T Cells (5)
E. coli (3)
HEK 293 Cells (6)
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Yeast (1)
Purified (1)
PRAME Antibody - MAPE Antibody (RB18763) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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PRAME Rabbit anti-Human Polyclonal (aa476-502) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PRAME Antibody - Immunofluorescence analysis of U2OS cells.
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PRAME Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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Yeast
His
59.9 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
6His, N-terminus
62 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PRAME Antibody - Western blot of PRAME in MCF7 cell lysate. Lane 1 shows pre-immune sera. Lane 2 shows antibody tested at 1:5000 dilution.
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PRAME Rabbit anti-Human Polyclonal Antibody
Dog, Bovine, Horse, Human, Monkey
WB
Unconjugated
100 µl/$386
PRAME Antibody - PRAME antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PRAME Antibody - PRAME antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Bovine, Rat, Pig, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PRAME Antibody - PRAME antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Bovine, Rat, Pig, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PRAME Antibody - PRAME antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Bovine, Rat, Pig, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
PRAME Antibody - Western blot of recombinant PRAME.
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PRAME Rabbit anti-Human Polyclonal (aa416-502) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PRAME Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (aa1-509) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PRAME Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (aa1-509) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
PRAME Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PRAME Rabbit anti-Human Polyclonal (aa1-509) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
PRAME Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (aa1-509) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
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PRAME Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$351
PRAME Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using PRAME Polyclonal Antibody at dilution of 1:65(×200)
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PRAME Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PRAME Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PRAME Antibody - Western blot analysis of extracts of HepG2 cells using PRAME antibody. The lane on the left was treated with blocking peptide.
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PRAME Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PRAME Antibody - PRAME antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRAME Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
PRAME Antibody - PRAME antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PRAME Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Pig, Horse, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
PRAME Antibody - PRAME antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PRAME Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Pig, Horse, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
PRAME Antibody - PRAME antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PRAME Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Pig, Horse, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
PRAME Antibody - Western blot analysis of extracts of various cell lines, using PRAME antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
Select
PRAME Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PRAME Antibody - Western blot of recombinant PRAME.
Select
PRAME Rabbit anti-Human Polyclonal (aa416-502) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PRAME Antibody - Western blot of recombinant PRAME.
Select
PRAME Rabbit anti-Human Polyclonal (aa416-502) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
Viewing 1-25 of 56 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).