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PQBP1

polyglutamine binding protein 1

Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

Gene Name: polyglutamine binding protein 1
Synonyms: PQBP1, MRX55, MRXS3, PQBP-1, MRXS8, NPW38, RENS1, SHS
Target Sequences: NM_005710 NP_005701.1 O60828

☰ Filters
Proteins (22)
Antibodies (19)
Over-Expression Lysate (12)
Primary (19)
Recombinant (10)
PQBP1 (41)
Human (19)
Mouse (6)
Rat (7)
Bovine (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (6)
Orangutan (6)
Pig (3)
Rabbit (3)
IHC (11)
IHC-P (8)
WB (15)
ELISA (6)
ICC (1)
IF (1)
IP (2)
rabbit (18)
mouse (1)
Product Group
IHCPlus (1)
IgG (17)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (18)
3H7 (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (10)
aa58-107 (4)
aa72-121 (4)
aa150-200 (1)
aa215-265 (1)
No (41)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (18)
Human (16)
293T Cells (6)
E. coli (1)
HEK 293 Cells (12)
Wheat Germ Extract (3)
Purified (1)
PQBP1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PQBP1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PQBP1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PQBP1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
PQBP1 Antibody - Immunofluorescence staining of PQBP1 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human PQBP1 polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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PQBP1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
PQBP1 Antibody - Detection of Human and Mouse PQBP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-PQBP1 used at a dilution of 1:200 (1 ug/mg).
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PQBP1 Rabbit anti-Human Polyclonal (aa215-265) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PQBP1 Antibody - Detection of Human and Mouse PQBP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-PQBP1 used at a dilution of 1:1000 (1 ug/mg).
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PQBP1 Rabbit anti-Human Polyclonal (aa150-200) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PQBP1 Antibody - PQBP1 antibody ARP31454_T100-PQBP1 (polyglutamine binding protein 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa58-107) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
PQBP1 Antibody - PQBP1 antibody ARP31454_T100-PQBP1 (polyglutamine binding protein 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PQBP1 Rabbit anti-Human Polyclonal (aa58-107) (HRP) Antibody
Rabbit, Mouse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
PQBP1 Antibody - PQBP1 antibody ARP31454_T100-PQBP1 (polyglutamine binding protein 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PQBP1 Rabbit anti-Human Polyclonal (aa58-107) (Biotin) Antibody
Rabbit, Mouse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
PQBP1 Antibody - PQBP1 antibody ARP31454_T100-PQBP1 (polyglutamine binding protein 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PQBP1 Rabbit anti-Human Polyclonal (aa58-107) (FITC) Antibody
Rabbit, Mouse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
PQBP1 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using PQBP1 Antibody at dilution of 1:100
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PQBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
PQBP1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PQBP1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PQBP1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PQBP1 Antibody - Detection limit for recombinant GST tagged PQBP1 is 0.03 ng/ml as a capture antibody.
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PQBP1 Mouse anti-Human Monoclonal (3H7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
PQBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
PQBP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PQBP1 Antibody
Select
PQBP1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
PQBP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.2 kDa
100 µg/$494
PQBP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PQBP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PQBP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
30.3 kDa
20 µg/$150
PQBP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
30.3 kDa
20 µg/$150
PQBP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
30.3 kDa
20 µg/$150
Viewing 1-25 of 41 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).