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PPT1 / CLN1

palmitoyl-protein thioesterase 1

PPT1 is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: palmitoyl-protein thioesterase 1
Synonyms: PPT1, CLN1, Palmitoyl-protein hydrolase 1, Palmitoyl-protein thioesterase, INCL, PPT-1, PPT
Target Sequences: NM_000310 NP_000301.1 P50897

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
PPT1 / CLN1 (10)
SDS-PAGE (1)
No (10)
6His, C-terminus (2)
GST (1)
His, N-Terminal (1)
His,C-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (3)
PPT1 / CLN1 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human PPT1 comprises 290 amino acids and has a predicted molecular mass of 32.7 kDa. The apparent molecular mass of the protein is approximately 35-41 kDa in SDS-PAGE under reducing conditions.
100 µg/$441
PPT1 / CLN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.09 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
32.3 kDa
10 µg/$368; 50 µg/$479
PPT1 / CLN1 Protein
Select
E. coli
His, N-Terminal
34.2 kDa
50 µg/$419
PPT1 / CLN1 Protein - 12.5% SDS-PAGE of human PPT1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
60.6 kDa
10 µg/$479; 25 µg/$670
PPT1 / CLN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.19 kDa
20 µg/$150
PPT1 / CLN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.09 kDa
20 µg/$150
PPT1 / CLN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.19 kDa
100 µg/$494
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
32.3kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
PPT1 / CLN1 Protein - Recombinant Palmitoyl Protein Thioesterase 1 By SDS-PAGE
Select
E. coli
His-T7
32.3 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).