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PPP6C

protein phosphatase 6, catalytic subunit

Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

Gene Name: protein phosphatase 6, catalytic subunit
Family/Subfamily: Protein Phosphatase , Protein Phosphatase - Serine/Threonine other
Synonyms: PPP6C, PP6, PP6C, PPP6, Protein phosphatase 6
Target Sequences: NM_002721 NP_002712.1 O00743

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
PPP6C (6)
No (6)
GST (1)
His,N-terminus (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
PPP6C Protein - Recombinant Protein Phosphatase 6, Catalytic Subunit (PPP6C) by SDS-PAGE
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E. coli
His,N-terminus
38.6kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
PPP6C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.8 kDa
20 µg/$150
PPP6C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.4 kDa
20 µg/$150
PPP6C Protein - 12.5% SDS-PAGE of human PPP6C stained with Coomassie Blue
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Wheat Germ Extract
GST
59.29 kDa
10 µg/$479; 25 µg/$670
PPP6C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.8 kDa
100 µg/$494
PPP6C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.4 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).