PPP2R4

protein phosphatase 2A activator, regulatory subunit 4

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+ (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg2+ (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

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Products

ELISA Kits (5)

Type

Custom (2)

Sandwich (3)

Target

PPP2R4 (5)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Bovine (1)

Format

96-Well Strip Plate (5)

Publications

No (5)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human PPP2R4 (Sandwich ELISA) ELISA Kit - LS-F67349

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse PPP2R4 (Custom) ELISA Kit - LS-F66015

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Human PPP2R4 (Sandwich ELISA) ELISA Kit - LS-F67052

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Bovine PPP2R4 (Custom) ELISA Kit - LS-F66348

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

Select

Rat PPP2R4 (Sandwich ELISA) ELISA Kit - LS-F9512

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$893

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