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PPP2R3C

protein phosphatase 2, regulatory subunit B'', gamma

PPP2R3C is a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.

Gene Name: protein phosphatase 2, regulatory subunit B'', gamma
Synonyms: PPP2R3C, G4-1, G5pr, C14orf10
Target Sequences: NM_017917 NP_060387.2 Q969Q6

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).