PPP1R9B / Spinophilin

protein phosphatase 1, regulatory subunit 9B

Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity). Required for hepatocyte growth factor (HGF)-induced cell migration.

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Products

Antibodies (13)

ELISA Kits (4)

Proteins (4)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (13)

Recombinant (2)

Sandwich (3)

Target

PPP1R9B / Spinophilin (21)

Reactivity

Human (14)

Mouse (4)

Rat (5)

Application

IHC (3)

WB (13)

ELISA (8)

IP (2)

Peptide-ELISA (1)

Host

rabbit (11)

rabbit-new zealand white (1)

sheep (1)

Isotype

IgG (10)

Clonality

polyclonal pc (13)

Format

96-Well Strip Plate (4)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (8)

Epitope

aa24-53 (7)

aa286-390 (1)

aa289-412 (1)

aa450-500 (1)

Publications

No (21)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Select

Rat PPP1R9B / Spinophilin (Sandwich ELISA) ELISA Kit - LS-F20255

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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PPP1R9B / Spinophilin Antibody (aa24-53) LS-C162085

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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PPP1R9B / Spinophilin Antibody LS-C753915

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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PPP1R9B / Spinophilin Antibody LS-C802338

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PPP1R9B / Spinophilin Antibody (aa450-500) LS-C829731

Antibody:

PPP1R9B / Spinophilin Rabbit-New Zealand White anti-Human Polyclonal (aa450-500) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

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PPP1R9B / Spinophilin Antibody (aa24-53) LS-C330000

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PPP1R9B / Spinophilin Antibody (aa24-53, Biotin) LS-C216923

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PPP1R9B / Spinophilin Antibody (aa24-53, FITC) LS-C216924

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PPP1R9B / Spinophilin Antibody (aa24-53, APC) LS-C216922

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PPP1R9B / Spinophilin Antibody (aa24-53, Azide-free, HRP) LS-C216925

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PPP1R9B / Spinophilin Antibody (aa24-53, PE) LS-C216926

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal (aa24-53) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

PPP1R9B / Spinophilin Antibody LS-C779473

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

PPP1R9B / Spinophilin Antibody (aa286-390) LS-C39221

Antibody:

PPP1R9B / Spinophilin Rabbit anti-Rat Polyclonal (aa286-390) Antibody

Reactivity:

Rat

Applications:

IP, WB

Format:

Unconjugated

Price:

200 µg/$930

Select

PPP1R9B / Spinophilin Antibody (aa289-412) LS-C184894

Antibody:

PPP1R9B / Spinophilin Sheep anti-Human Polyclonal (aa289-412) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$919

Select

Human PPP1R9B / Spinophilin Protein (Recombinant GST, N-terminus) (aa708-817) - LS-G63394

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human PPP1R9B / Spinophilin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70913

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.2 kDa

Price:

20 µg/$1,107

Select

Human PPP1R9B / Spinophilin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88304

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.2 kDa

Price:

20 µg/$215

Select

Mouse PPP1R9B / Spinophilin (Custom ELISA) ELISA Kit - LS-F20256

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human PPP1R9B / Spinophilin (Sandwich ELISA) ELISA Kit - LS-F35958

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

PPP1R9B / Spinophilin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108708

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.2 kDa

Price:

100 µg/$710

Select

Human PPP1R9B / Spinophilin (Sandwich ELISA) ELISA Kit - LS-F12132

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Viewing 1-21 of 21 product results

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