PPP1R15A / GADD34

protein phosphatase 1, regulatory subunit 15A

Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

PPP1R15A / GADD34 (7)

Publications

No (7)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human PPP1R15A / GADD34 Protein (Recombinant 6His, N-terminus) (aa40-674) - LS-G57238

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Human PPP1R15A / GADD34 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87280

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.3 kDa

Price:

20 µg/$150

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PPP1R15A / GADD34 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114023

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.3 kDa

Price:

100 µg/$494

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Mouse PPP1R15A / GADD34 Protein (Recombinant His-T7) (aa433-636) - LS-G24681

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.8 kDa

Price:

10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Rat PPP1R15A / GADD34 Protein (Recombinant His-T7) (aa335-578) - LS-G24682

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.7 kDa

Price:

10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Human PPP1R15A / GADD34 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70507

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.3 kDa

Price:

20 µg/$1,107

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Human PPP1R15A / GADD34 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G62051

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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