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PPP1R13L / iASPP
protein phosphatase 1, regulatory subunit 13 like
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
| Gene Name: | protein phosphatase 1, regulatory subunit 13 like |
| Synonyms: | PPP1R13L, IASPP, Inhibitor of ASPP protein, NFkB-interacting protein 1, NKIP1, RAI4, RAI, Retinoic acid induced 4, NFkB interacting protein 1, PPP1R13BL, Protein iASPP, RelA-associated inhibitor, PPP1R13B-like protein |
| Target Sequences: | NM_006663 NP_006654.2 Q8WUF5 |
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