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PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.
| Gene Name: | protein phosphatase 1, catalytic subunit, beta isozyme |
| Family/Subfamily: | Protein Phosphatase , PP1 |
| Synonyms: | PPP1CB, PP-1B, pp1 delta, PPP1CD, Protein phosphatase 1-beta, Protein phosphatase 1-delta, PP1beta, PP1 beta |
| Target Sequences: | NM_002709 NP_002700.1 P62140 |
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