PPM1F

protein phosphatase, Mg2+/Mn2+ dependent, 1F

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PPM1F (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human PPM1F Protein (Recombinant GST) (Full Length) - LS-G31748

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PPM1F Protein (Recombinant His) - LS-G2498

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human PPM1F Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66774

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.7 kDa

Price:

20 µg/$1,107

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Human PPM1F Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G61211

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PPM1F Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78477

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.7 kDa

Price:

20 µg/$150

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PPM1F Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101242

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.7 kDa

Price:

100 µg/$494

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