Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
PPM1A / PP2CA
protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1A / PP2CA is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
| Gene Name: | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| Family/Subfamily: | Protein Phosphatase , PP2C |
| Synonyms: | PPM1A, PP2Calpha, Protein phosphatase 1A, Protein phosphatase 2C alpha, Protein phosphatase IA, PP2CA, PPPM1A, PP2C-ALPHA |
| Target Sequences: | NM_021003 NP_066283.1 P35813 |
☰ Filters
Products
Antibodies
(38)
Proteins
(12)
ELISA Kits
(2)
Type
Over-Expression Lysate
(4)
Primary
(38)
Recombinant
(8)
Sandwich
(2)
Target
PPM1A / PP2CA
(52)
Reactivity
Human
(35)
Mouse
(11)
Rat
(8)
Bat
(3)
Bovine
(3)
Chicken
(3)
Chimpanzee
(3)
Dog
(3)
Gibbon
(3)
Guinea pig
(3)
Hamster
(3)
Horse
(3)
Non-Human Primate
(1)
Orangutan
(3)
Pig
(11)
Rabbit
(3)
Xenopus
(3)
Application
IHC
(3)
IHC-P
(4)
WB
(32)
Flo
(5)
ELISA
(15)
ICC
(3)
IF
(4)
IP
(2)
Host
rabbit
(30)
mouse
(8)
Product Group
IHCPlus
(1)
Isotype
IgG
(13)
IgG1
(3)
IgG2a,k
(1)
Clonality
monoclonal mc
(8)
polyclonal pc
(30)
Clone
4E11
(1)
7F12
(1)
7F12H6
(1)
Format
96-Well Strip Plate
(2)
APC
(1)
APC Conjugated
(2)
Azide-free
(1)
Biotin Conjugated
(3)
Cy3 Conjugated
(1)
Cy7 Conjugated
(1)
FITC Conjugated
(4)
HRP Conjugated
(3)
PE Conjugated
(3)
Preservative Free
(2)
Unconjugated
(21)
Epitope
aa2-382
(8)
aa355-382
(7)
aa107-156
(4)
Amino Acid: 202-382
(1)
aa1-324
(1)
Publications
No
(52)
Sample Type
Cell Lysates
(2)
Tissue Homogenates
(2)
Tag
6His, C-terminus
(2)
GST
(1)
GST, N-terminus
(1)
His
(2)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Human
(9)
Mouse
(1)
Source
293T Cells
(2)
E. coli
(6)
HEK 293 Cells
(3)
Wheat Germ Extract
(1)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(3)
Biologically Active
Biologically active
(1)
PPM1A / PP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PPM1A / PP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PPM1A / PP2CA Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µl/$412
PPM1A / PP2CA Mouse anti-Human Monoclonal (4E11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PPM1A / PP2CA Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated, Preservative Free
50 µl/$317; 100 µl/$375; 200 µl/$473
PPM1A / PP2CA Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
PPM1A / PP2CA Mouse anti-Human Monoclonal (7F12H6) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
PPM1A / PP2CA Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
PPM1A / PP2CA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PPM1A / PP2CA Mouse anti-Human Monoclonal (Amino Acid: 202-382) (7F12) Antibody
Mouse, Human, Non-Human Primate
Flo, WB
Unconjugated
100 µg/$503
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PPM1A / PP2CA Rabbit anti-Human Polyclonal (aa355-382) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PPM1A / PP2CA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
PPM1A / PP2CA Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
PPM1A / PP2CA Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
PPM1A / PP2CA Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$412
PPM1A / PP2CA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
PPM1A / PP2CA Mouse anti-Human Monoclonal (aa1-324) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$884
PPM1A / PP2CA Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
25 Tests/$293; 100 Tests/$376
PPM1A / PP2CA Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
Viewing 1-25
of 52
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
