PPIP5K2 / HISPPD1

diphosphoinositol pentakisphosphate kinase 2

Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4.

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Proteins (1)

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Recombinant (1)

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PPIP5K2 / HISPPD1 (1)

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Tag

His, N-Terminal (1)

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Human (1)

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E. coli (1)

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Human PPIP5K2 / HISPPD1 Protein (Recombinant His, N-Terminal) - LS-G145021

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

137.9 kDa

Price:

50 µg/$419

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