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PPIH / Cyclophilin H
peptidylprolyl isomerase H (cyclophilin H)
PPIH / Cyclophilin H is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
| Gene Name: | peptidylprolyl isomerase H (cyclophilin H) |
| Synonyms: | PPIH, Cyclophilin H, CYP-20, CYP20, PPIase H, Rotamase H, USA-CYP, CYPH, SnuCyp-20, USA-CyP SnuCyp-20 |
| Target Sequences: | NM_006347 NP_006338.1 O43447 |
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