PPIF / Cyclophilin F

peptidylprolyl isomerase F

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

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Products

ELISA Kits (8)

Type

Cell-Based (1)

Competitive EIA (1)

Custom (4)

Sandwich (2)

Target

PPIF / Cyclophilin F (8)

Reactivity

Human (3)

Mouse (3)

Rat (3)

Bovine (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

Publications

No (8)

Sample Type

Adherent Cell Cultures (1)

Plasma (3)

Serum (3)

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Mouse PPIF / Cyclophilin F (Custom) ELISA Kit - LS-F65303

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Rat PPIF / Cyclophilin F (Custom) ELISA Kit - LS-F65420

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

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Bovine PPIF / Cyclophilin F (Custom) ELISA Kit - LS-F65772

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

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Human PPIF / Cyclophilin F (Custom) ELISA Kit - LS-F66049

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$783

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Human PPIF / Cyclophilin F (Sandwich ELISA) ELISA Kit - LS-F26771

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Rat PPIF / Cyclophilin F (Sandwich ELISA) ELISA Kit - LS-F27392

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

100 - 2500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse PPIF / Cyclophilin F (Competitive EIA) ELISA Kit - LS-F28114

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse/Human/Rat PPIF / Cyclophilin F (Cell-Based ELISA) ELISA Kit - LS-F3084

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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