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PPEF / PPEF1

protein phosphatase, EF-hand calcium binding domain 1

PPEF-1, a RdgC type serine/threonine phosphatase, is homologous to the Drosophila retinal degeneration C gene (rdgc) which is required to prevent light-induced retinal degeneration. However, elimination of PPEF function does not result in retinal degeneration in vertebrates. PPEF/RdgC subfamily members are characterized by C-terminal EF-hands (i. e., two or more EF-hand calcium-binding motifs). Mammalian PPEF proteins are expressed mainly within the nervous system and enriched in a subset of primary sensory neurons. They are believed to regulate calcium-dependent rhodopsin dephosphorylation. At least five PPEF-1 isoforms have been identified.

Gene Name: protein phosphatase, EF-hand calcium binding domain 1
Family/Subfamily: Protein Phosphatase , RdgC
Synonyms: PPEF1, PPEF, PPP7C, PP7, PPEF-1, PPP7CA, Protein phosphatase PP7
Target Sequences: NM_006240 NP_006231.2 O14829

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Proteins (7)
Over-Expression Lysate (6)
Recombinant (1)
PPEF / PPEF1 (7)
No (7)
GST (1)
Myc-DDK (Flag) (6)
Human (4)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.5 kDa
100 µg/$710
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68.6 kDa
100 µg/$710
PPEF / PPEF1 Protein - 12.5% SDS-PAGE of human PPEF1 stained with Coomassie Blue
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Wheat Germ Extract
GST
97.57 kDa
10 µg/$479; 25 µg/$670
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
75.6 kDa
20 µg/$150
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68.6 kDa
20 µg/$215
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
72.5 kDa
20 µg/$215
PPEF / PPEF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
75.6 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).