PPARG / PPAR Gamma

peroxisome proliferator-activated receptor gamma

Peroxisome proliferator-activated receptor gamma (PPAR gamma), a NR1 Thyroid Hormone-Like Receptor, is a transcription factor that regulates genes involved in lipid metabolism and adipocyte differentiation and has been shown to affect placental differentiation and cell proliferation and differentiation pathways in various diseases such as Type II diabetes and atherosclerosis. Recently, PPAR gamma has been suggested to affect inflammatory digestive diseases (Dubuquoy et al. 2002). PPAR gamma binds target DNA as a heterodimer (with retinoid X receptors) and has several coactivators, including steroid receptor coactivator-1 (SRC-1) and PPAR-binding protein (PBP). Two isoforms of PPAR gamma protein have been identified: PPAR gamma2 contains 30 additional amino acids at the N terminus compared to PPAR gamma1. PPAR gamma2 is expressed mainly in adipose tissue, whereas PPAR gamma1 is expressed widely. Mutations in PPAR gamma2 have been implicated in the development of obesity and Type II diabetes. PPAR gamma is the molecular target of thiazolidinediones (TZDs), drugs used widely for treatment of Type II diabetes, and is believed to mediate the apoptotic effects of this class of drugs in a variety of cell types, including B and T lymphocytes. Altered expression of PPAR gamma and cyclooxygenase-2 (COX-2) and the subsequent modulation in the tissue levels of PGE(2) and 15-d-PGJ(2) may influence the development of human breast cancer and its progression to metastasis.

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Products

ELISA Kits (35)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (2)

Development Kit (3)

DNA Binding (1)

Sandwich (23)

Sandwich CLIA (4)

Target

PPARG / PPAR Gamma (35)

Reactivity

Human (9)

Mouse (10)

Rat (12)

Bovine (1)

Chicken (1)

Dog (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (2)

Sheep (1)

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Product Group

DevKit DuoPlus (3)

Format

12 x 8-Well Microstrips (5)

96-Well Microplate (5)

96-Well Strip Plate (22)

Antibody Pair and Standard (3)

Publications

No (35)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (8)

Cell Lysates (9)

Nuclear Lysates (1)

Plasma (24)

Serum (24)

Tissue Homogenates (13)

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Human PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F12376

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F4265

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Rat PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F4266

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Mouse PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F4267

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Rat PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F15392

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Pig PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F15391

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse/Human/Rat PPARG / PPAR Gamma (Cell-Based ELISA) ELISA Kit - LS-F2267

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Rabbit PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F9286

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

Select

Mouse/Human/Rat PPARG / PPAR Gamma (DNA-Binding ELISA) ELISA Kit - LS-F792

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Rat PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F51061

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,100

Select

Mouse PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F50992

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.625 - 40 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,081

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Rat PPARG / PPAR Gamma (CLIA) ELISA Kit - LS-F40488

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Chicken PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46612

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Monkey PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Porcine PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46615

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Guinea pig PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46614

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rabbit PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46616

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Sheep PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F46617

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

Select

Human PPARG / PPAR Gamma (Sandwich ELISA) ELISA Kit - LS-F50946

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,041

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DevKit DuoPlus Human PPARG / PPAR Gamma ELISA Development Kit - LS-F71611

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,182; 1000 Wells/$1,747

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DevKit DuoPlus Mouse PPARG / PPAR Gamma ELISA Development Kit - LS-F71708

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,207; 1000 Wells/$1,787

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DevKit DuoPlus Rat PPARG / PPAR Gamma ELISA Development Kit - LS-F71899

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,254; 1000 Wells/$1,867

Select

Rat PPARG / PPAR Gamma (CLIA) ELISA Kit - LS-F40570

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Dog PPARG / PPAR Gamma (Custom ELISA) ELISA Kit - LS-F15393

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

Select

Mouse PPARG / PPAR Gamma (Custom ELISA) ELISA Kit - LS-F15394

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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