Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

PPARD / PPAR Delta

peroxisome proliferator-activated receptor delta

PPARD / PPAR Delta is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.

Gene Name: peroxisome proliferator-activated receptor delta
Family/Subfamily: NHR , NR1 Thyroid hormone-like
Synonyms: PPARD, FAAR, NUCI, PPAR-beta, PPAR-delta, NR1C2, NUC1, NUCII, Nuclear hormone receptor 1, PPARB, PPAR Delta
Target Sequences: NM_006238 NP_006229.1 Q03181

Publications (1)

1
Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus. Chen H, Li J, Li H, Hu Y, Tevebaugh W, Yamamoto M, Que J, Chen X. PloS one. 2012 7:e36504. (IHC-P; Mouse) [Full Text Article] [PubMed:22567161] [PMC:PMC3342176] Related Antibodies: LS-B45.

Viewing 1-25 of 86 items
PPARD / PPAR Delta Antibody - Anti-PPAR Delta antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
(1) Publication(s)
Rabbit Polyclonal to Mouse PPARD / PPAR Delta
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
PPARD / PPAR Delta Antibody - Anti-PPAR Delta antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Select
Goat Polyclonal to Human PPARD / PPAR Delta
Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
PPARD / PPAR Delta Antibody - Anti-PPAR Delta antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Dog, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
1ea   $425.00
PPARD / PPAR Delta Antibody - Immunofluorescence analysis of PPAR delta was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. The cells were labeled with PPAR delta Rabbit Polyclonal Antibody and progenitors ( b, Lgr5-GFP low ) required less Wnt3a and R-spondin to initiate organoids compared to C ISCs as measured by comparing organoid-formation in complete ENRW media, which includes EGF, Noggin, R-spondin, and Wnt3a, versus EN media, which includes EGF and Noggin but lacks Wnt3a and R-spondin ( n =3). C-derived progenitors, in contrast to HFD-derived progenitors, rarely formed organoids in either ENRW or EN media. c-f, HFD increased nuclear beta-catenin localization in flow sorted ISCs and progenitors from HFD ( c, n =5) and GW-treated ( d, n =4) mice as determined by immunofluorescence (red=DAPI, cyan=non-phosphorylated beta-catenin, CST 8814S). At least 100 cells per sample were quantified. Representative images are shown in ( e, f ). g - i, HFD ( g ) and GW ( h ) treatment increased the numbers of ISCs and progenitors with beta-catenin + nuclei as assessed by immunostains ( n =4 each). Representative images are shown in ( i ) arrowheads indicate representative nuclear beta-catenin in ISCs (red) and progenitors (black). j - l, Association of PPAR-d and beta-catenin in C and HFD derived intestinal crypts as shown by immunoprecipitation (IP)
Select
Rabbit Polyclonal (IgG) to Mouse PPARD / PPAR Delta
Mouse, Rat, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100µl   1mg/ml   $445.00
PPARD / PPAR Delta Antibody - Immunofluorescence analysis of U20S cells.
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Mouse, Human
IF, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
PPARD / PPAR Delta Antibody - LN18 Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $335.00
PPARD / PPAR Delta Antibody - LN18 Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl   1mg/ml   $355.00
PPARD / PPAR Delta Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Mouse Monoclonal (IgG1) to Human PPARD / PPAR Delta
Human
ELISA, IHC, WB
Unconjugated
100µg   $355.00
PPARD / PPAR Delta Antibody - Immunohistochemical staining of paraffin-embedded Human adult brain tissue within the normal limits using anti-PPARD mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
Select
Mouse Monoclonal [clone OTI4D10] (IgG1) to Human PPARD / PPAR Delta
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $345.00
PPARD / PPAR Delta Antibody - Immunohistochemical staining of paraffin-embedded Human adult brain tissue within the normal limits using anti-PPARD mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
Select
Mouse Monoclonal [clone OTI4D10] (IgG1) to Human PPARD / PPAR Delta
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, IHC, WB
Unconjugated
100µg   $355.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Human
ELISA, Flo, WB
PE Conjugated
200µl   $740.00
PPARD / PPAR Delta Antibody - Immunohistochemical analysis of human-liver tissue. Anti-PPAR Delta at 1:200 (4°C, overnight). Antigen retrieval - Sodium Citrate pH6 (>98°C, 20min). Secondary - 1:200 (room temp, 30min). Negative control - Secondary only
Select
Mouse Monoclonal (IgG1) to Human PPARD / PPAR Delta
Mouse, Rat, Human
IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal to Human PPARD / PPAR Delta
Mouse, Rat, Human
IF, WB
Unconjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human PPARD / PPAR Delta
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Mouse Monoclonal [clone 5F4] (IgG) to Human PPARD / PPAR Delta
Mouse, Rat, Human
IF, IHC-P
Unconjugated
20µl   1mg/ml   $205.00; 60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Mouse PPARD / PPAR Delta
Mouse
ELISA, WB
Unconjugated
50µg   $375.00
PPARD / PPAR Delta Antibody - PPARD Antibody western blot of HepG2 cell line lysates (35 ug/lane). The PPARD antibody detected the PPARD protein (arrow).
Select
Rabbit Polyclonal to Human PPARD / PPAR Delta
Human
Flo, WB
Unconjugated
400µl   $325.00

Viewing 1-25 of 86 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).