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POSTN / Periostin

periostin, osteoblast specific factor

Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.

Gene Name: periostin, osteoblast specific factor
Synonyms: POSTN, OSF2, PDLPOSTN, Periostin isoform thy6, Periostin isoform thy8, RP11-412K4.1, OSF-2, Osteoblast-specific factor 2, Periostin, Periostin isoform thy2, Periostin isoform thy4, PN
Target Sequences: NM_006475 NP_006466.2 Q15063

Publications (4)

1
Combined cardiomyocyte PKCd and PKCe gene deletion uncovers their central role in restraining developmental and reactive heart growth. Song M, Matkovich SJ, Zhang Y, Hammer DJ, Dorn GW nd. Science signaling. 2015 8:ra39. (IHC; Mouse) [Full Text Article] [PubMed:25900833] [PMC:PMC4677479] Related Antibodies: LS-C150337.
2
Periostin overexpression is associated with worse prognosis in nasopharyngeal carcinoma from endemic area: a cohort study. Wei YC, Yang SF, Chang SL, Chen TJ, Lee SW, Chen HS, Lin LC, Li CF. OncoTargets and therapy. 2018 May;11:3205-3213. (Human) [Full Text Article] [PubMed:29881294] [PMC:PMC5985804] Related Antibodies: LS-B3986.
3
SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation. Natalie M Landry , Sunil G Rattan , Krista L Filomeno , Thomas W Meier , Simon C Meier , Sarah J Foran, Claire F Meier, Navid Koleini , Robert R Fandrich, Elissavet Kardami , Todd A Duhamel , Ian M C Dixon. Basic research in cardiology. 2021 Apr;116:25. [Full Text Article] [PubMed:33847835] [PMC:PMC8043893] Related Antibodies: LS-B10443.
4
Role of Periostin Expression in Canine Osteosarcoma Biology and Clinical Outcome. Lauren N Alfino, Kai C Wilczewski-Shirai, Kathryn E Cronise, Jonathan Coy, Kristina Glapa, E J Ehrhart, Joseph B Charles, Dawn L Duval, Daniel P Regan. Veterinary pathology. 2021 September;58:981-993. [Full Text Article] [PubMed:33685296] [PMC:PMC8426451] Related Antibodies: LS-B3986.
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Products
Proteins (19)
Over-Expression Lysate (2)
Recombinant (17)
POSTN / Periostin (19)
No (19)
6His, C-terminus (2)
DDK (Flag) (1)
DDK,C-terminus (1)
His (8)
His, N-terminus (1)
His,C-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (11)
Mouse (5)
Rat (2)
293T Cells (1)
CHO Cells (2)
E. coli (9)
HEK 293 Cells (5)
Human Cells (1)
Mammalian Cells (1)
Purified (2)
Low endotoxin level (8)
Select
CHO Cells
DDK (Flag)
Less than 0.1 EU/µg protein (determined by LAL method).
~85kDa
10 µg/$309
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His-T7
18.4 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,881
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His
16.4 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
POSTN / Periostin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
87.1 kDa
100 µg/$710
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
89 kDa
100 µg/$721
POSTN / Periostin Protein - Recombinant Human POSTN Protein (His Tag)-Elabscience
Select
E. coli
His, N-terminus
38 kDa
20 µg/$270; 100 µg/$390
POSTN / Periostin Protein - Purified recombinant protein POSTN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
86.8 kDa
20 µg/$1,107
POSTN / Periostin Protein - Purified recombinant protein POSTN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
87.1 kDa
20 µg/$1,107
POSTN / Periostin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
87.1 kDa
20 µg/$215
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
86 kDa
100 µg/$721
Select
E. coli
153 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
16.94 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
85.6kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
CHO Cells
DDK,C-terminus
Less than 0.01 EU/µg protein (determined by LAL method).
~75 kDa
10 µg/$309
Select
E. coli
164 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
18.15 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
85.6 kDa
10 µg/$281; 50 µg/$389
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His
16.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His
18.4 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His
18.7 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
POSTN / Periostin Protein - Recombinant Periostin By SDS-PAGE
Select
E. coli
His
15.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).