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PON3

paraoxonase 3

PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.

Gene Name: paraoxonase 3
Synonyms: PON3, Paraoxonase 3, Paraoxanase-3, Serum paraoxonase/lactonase 3
Target Sequences: L48516 AAC41996.1 Q15166

Publications (1)

1
Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice. Sarah L Kempster, Gusztav Belteki, Diana Licence, D Stephen Charnock-Jones, Gordon C S Smith. The Breast : official journal of the European Society of Mastology. 2012 Jan;302:E103-7. [Full Text Article] [PubMed:21952037] Related Antibodies: LS-C38071.

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ELISA Kits (11)
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PON3 (11)
Human (5)
Mouse (1)
Rat (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (9)
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Plasma (5)
Serum (5)
Tissue Homogenates (1)
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PON3 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.23 - 15 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.234 - 15 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.234 - 15 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
93.75 - 6000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
PON3 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
PON3 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
PON3 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
46.875 - 3000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PON3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.234 - 15 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PON3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).