POLR3E / SIN

polymerase (RNA) III (DNA directed) polypeptide E (80kD)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Products

Antibodies (14)

Type

Primary (14)

Target

POLR3E / SIN (14)

Reactivity

Human (14)

Mouse (3)

Monkey (1)

Application

IHC (8)

IHC-P (2)

WB (7)

ELISA (6)

ICC (2)

IF (5)

IP (3)

Peptide-ELISA (2)

Host

rabbit (13)

mouse (1)

Isotype

IgG (12)

IgG2b (1)

Clonality

monoclonal mc (1)

polyclonal pc (13)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (11)

Epitope

160-240 aa, Internal (1)

Internal (1)

aa175-225 (1)

aa191-240 (1)

aa475-525 (1)

Publications

No (14)

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POLR3E / SIN Antibody (Internal) LS-C368900

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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POLR3E / SIN Antibody (160-240 aa, Internal) LS-C385585

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (160-240 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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POLR3E / SIN Antibody (aa191-240) LS-C119920

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (aa191-240) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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POLR3E / SIN Antibody LS-C824045

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$357

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POLR3E / SIN Antibody LS-C155686

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$450

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POLR3E / SIN Antibody LS-C379502

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3E / SIN Antibody (HRP) LS-C379510

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3E / SIN Antibody (Biotin) LS-C379509

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3E / SIN Antibody (FITC) LS-C379511

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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POLR3E / SIN Antibody (aa475-525) LS-C290366

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (aa475-525) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

POLR3E / SIN Antibody LS-C801804

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

POLR3E / SIN Antibody LS-C817013

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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POLR3E / SIN Antibody LS-C126144

Antibody:

POLR3E / SIN Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

POLR3E / SIN Antibody (aa175-225) LS-C290364

Antibody:

POLR3E / SIN Rabbit anti-Human Polyclonal (aa175-225) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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