POLR3D

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

POLR3D (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human POLR3D Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65086

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

20 µg/$1,107

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Human POLR3D Protein (Recombinant GST, N-terminus) (aa296-395) - LS-G57916

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human POLR3D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74799

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

20 µg/$150

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Human POLR3D Protein (Recombinant GST) (Full Length) - LS-G27646

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.8 kDa

Price:

2 µg/$439

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POLR3D Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99533

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

100 µg/$494

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