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POLR3D

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Gene Name: polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Synonyms: POLR3D, Protein BN51, RNA polymerase III subunit C4, RPC4, RPC53 homolog, TSBN51, BN51, BN51T, RPC53
Target Sequences: NM_001722 NP_001713.2 P05423

☰ Filters
Products
Antibodies (17)
Primary (17)
POLR3D (17)
Human (17)
Mouse (5)
IHC (2)
WB (15)
ELISA (10)
IF (1)
IP (1)
Peptide-ELISA (3)
rabbit (16)
mouse (1)
IgG (15)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (16)
4E6 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa127-156 (7)
aa175-225 (2)
250-330 aa, C-terminal (1)
aa265-314 (1)
aa281-330 (1)
aa348-398 (1)
No (17)
POLR3D Antibody - Detection of Human POLR3D by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-POLR3D used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
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POLR3D Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
POLR3D Antibody - Staining MCF-7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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POLR3D Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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POLR3D Rabbit anti-Human Polyclonal (aa127-156) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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POLR3D Rabbit anti-Human Polyclonal (aa127-156) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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POLR3D Rabbit anti-Human Polyclonal (aa127-156) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
POLR3D Rabbit anti-Human Polyclonal (aa127-156) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
POLR3D Rabbit anti-Human Polyclonal (aa127-156) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
POLR3D Rabbit anti-Human Polyclonal (aa127-156) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
POLR3D Rabbit anti-Human Polyclonal (250-330 aa, C-terminal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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POLR3D Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
POLR3D Antibody - Western blot analysis of extracts from MCF-7 cells, using RPC4 antibody.
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POLR3D Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
POLR3D Antibody - Western blot analysis of lysates from MCF-7 cells, using RPC4 Antibody. The lane on the right is blocked with the synthesized peptide.
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POLR3D Rabbit anti-Human Polyclonal (aa281-330) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
POLR3D Antibody - Western blot analysis of the lysates from HepG2 cells using RPC4 antibody.
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POLR3D Rabbit anti-Human Polyclonal (aa265-314) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
POLR3D Antibody - Detection of Human POLR3D by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-POLR3D used at a dilution of 1:100.
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POLR3D Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IHC
Unconjugated
1 µg/$295; 100 µl/$532
POLR3D Antibody - Detection limit for recombinant GST tagged POLR3D is approximately 0.3 ng/ml as a capture antibody.
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POLR3D Mouse anti-Human Monoclonal (4E6) Antibody
Human
ELISA
Unconjugated
100 µg/$423
POLR3D Antibody - POLR3D Antibody western blot of 293 cell line lysates (35 ug/lane). The POLR3D antibody detected the POLR3D protein (arrow).
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POLR3D Rabbit anti-Human Polyclonal (aa127-156) Antibody
Human
WB
Unconjugated
400 µl/$393
POLR3D Antibody - Detection of Human POLR3D by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-POLR3D antibody used for WB at 0.1 ug/ml Detection: Chemiluminescence with an exposure time of 3 minutes.
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POLR3D Rabbit anti-Human Polyclonal (aa348-398) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).