POLR2G / RPB7

polymerase (RNA) II (DNA directed) polypeptide G

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

POLR2G / RPB7 (5)

Publications

No (5)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Rabies Virus (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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POLR2G / RPB7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117816

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.1 kDa

Price:

100 µg/$494

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Human POLR2G / RPB7 Protein (Recombinant GST) (Full Length) - LS-G29808

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human POLR2G / RPB7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75600

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.1 kDa

Price:

20 µg/$150

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Rabies Virus POLR2G / RPB7 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa20-459) - LS-G56684

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human POLR2G / RPB7 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G59666

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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