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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
Gene Name: | polymerase (RNA) I polypeptide E, 53kDa |
Synonyms: | POLR1E, PRAF1, RNA polymerase I subunit A49, PAF53, RP11-405L18.3 |
Target Sequences: | NM_022490 NP_071935.1 Q9GZS1 |
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