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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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POLD3
polymerase (DNA-directed), delta 3, accessory subunit
POLD3 is the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.
| Gene Name: | polymerase (DNA-directed), delta 3, accessory subunit |
| Synonyms: | POLD3, DNA polymerase delta subunit 3, KIAA0039, p66, p68, Pol delta C subunit (p66) |
| Target Sequences: | D26018 BAA05039.1 Q15054 |
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