PNPLA1

patatin-like phospholipase domain containing 1

PNPLA1 belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Proteins (4)

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Over-Expression Lysate (4)

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PNPLA1 (4)

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Myc-DDK (Flag) (4)

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Human (2)

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293T Cells (2)

HEK 293 Cells (2)

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PNPLA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126806

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

100 µg/$494

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PNPLA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105285

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

100 µg/$710

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Human PNPLA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93995

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.7 kDa

Price:

20 µg/$150

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Human PNPLA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93996

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

20 µg/$215

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